CANADIAN CONSORTIUM ON STATISTICAL GENOMICS

Research

PROJECT DESCRIPTION
EVENTS

Project Description:

The project will focus on the large and high-dimensional data emerging from microarray experiments (DNA chips, proteome chips, etc.). Beyond the challenges of this data in itself, one must also incorporate large amounts of heterogeneous information from auxiliary sources, such as large public databases of gene and protein properties. With huge volumes of data, algorithmic and computability issues become increasingly important.
The experience of the research team brings together several broad fields of importance in statistical genomics: design of experiments; computation with and visualization of complex data; dimension reduction; and the statistical analysis of large correlated datasets. The program revolves around a significant multi-centre project funded by the Government of Ontario. This project, headed by Dr. Brent Zanke is here simply called the Tumour Bank. it involves the collection of a large number of cancer tissue samples frozen in liquid nitrogen, together with a comprehensive set of clinical and patient information. It is housed administratively in the Ontario Cancer Research network. One of its aims is to spur follow-up projects that will combine genomic experiments on the tissue samples with related clinical information. For example, SNP chip analysis of hundreds of colon cancer samples matched with controls.

Events:

The following event(s) had components associated with the project:

• September 3-5, 2003. Workshop on Statistical Genomics, Fields Institute, Toronto.
  

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