2020 Systems Modelling in the Pharmaceutical Industry - Problem Solving Workshop
Description
This workshop aims to equip graduate students and postdoctoral fellows in mathematics and related disciplines with the tools necessary to solve common problems encountered in the pharmaceutical industry. The focus will be on development of pharmacometric skills to approach questions centred on drug development and dose/therapy optimization using a variety of state-of-the-art quantitative systems pharmacology (QSP) methodologies. Participants will receive training in QSP approaches, including the principles of pharmacokinetics and pharmacodynamics (PK/PD), from academic and industrial researchers, and will apply these techniques in groups to solve a set of problems brought by industry partners. At the end of the week, participants will be able to identify the main components of a pharmaceutical problem through a QSP lens, translate these elements mathematically, analyze/numerically implement and solve the resulting mathematical model, and deliver results (visually and textually) to non-mathematicians. Ultimately, participants will gain understanding into the factors that are key to mathematical modelling in the pharmaceutical industry and be trained in modern QSP approaches.
Due to Covid-19, this year we are holding a virtual seminar event on July 16 12.00-15.00 instead of one-week in-person workshop. Any plans for future one-week workshop in the summer of 2021 will be announced later in the year.
Workshop application
Please note this workshop is aimed for upper-level undergraduates, graduate students, and postdocs. However, due to the online nature of this year’s half a day virtual workshop, registration is open to anyone to whom this may be of interest.
This event was not recorded in the interest of confidentiality.
Sponsors
Schedule
12:00 to 12:05 |
Opening Remarks
Morgan Craig, Université de Montréal, Anna Sher, Pfizer, Siv Sivaloganathan, University of Waterloo |
12:05 to 12:30 |
Introduction to Pharmacokinetics and Pharmacodynamics (PK/PD)
Timothy Nicholas, Pfizer |
12:30 to 12:55 |
Introduction to Quantitative Systems Pharmacology (QSP)
Anna Sher, Pfizer, Anna Kirpichnikova, University of Stirling |
12:55 to 13:00 |
Break
|
13:00 to 13:25 |
Real world application: QSP bone modelling
Mark Peterson, Vertex Pharmaceuticals |
13:25 to 13:50 |
Case studies combining QSP and PK/PD
Irina Kareva, EMD Serono, Merck KGaA |
13:50 to 14:00 |
Break
|
14:00 to 15:00 |
Panel discussion on QSP careers in industry
Panel members: Bart Borek, Vertex Pharmaceuticals; Irina Kareva, EMD Serono, Merck KGaA; Timothy Nicolas, Pfizer; Mark Peterson, Vertex Pharmaceuticals; Anna Sher, Pfizer. Moderator: Morgan Craig, Université de Montréal |