Electroporation-based therapies (EPT) consist in applying high voltage short pulses to cells (typically several hundred volts per centimeter during about one hundred microseconds) in order to create defects in the plasma membrane. They provide interesting alternatives to standard ablative techniques, in particular for deep seated located tumors (near vital organs or important vessels). However their use and their evaluation are still controversial in clinics. We present here a clinical workflow combined with numerical studies dedicated to IRE ablation. The clinical data consist on the one hand of a pre-treatment CT-scan, a C-arm Cone Beam CT with the electrodes and the post-treatment MR performed 3days after the IRE. On the other hand, chronograms of the electric intensity measured during the treatments are available. This study focused on one specific patient paves the way of augmented reality tools to evaluate a priori the IRE ablation efficacy thanks to advanced medical registration tool and appropriate electroporation models.